Discovered in the early 1940s, the endocannabinoid system is a biological system composed of endocannabinoids that are neurotransmitters that bind to cannabinoid receptors in the mammalian brain and body. CBD is one of the primary cannabinoids found in hemp.
These cannabinoid receptors play a pivotal role in physiological processes such as mood, memory and pain. There are two cannabinoid receptors - CB1 and CB2 that are located on cells throughout the body.
What are CB1 and CB2 receptors? CB1 receptors are primarily located on nerve cells in the brain, spinal cord and central nervous system. They are very abundant in the cerebellum, basal ganglia, and hippocampus. The CB1 receptors have been found to play a role in memory processing, motor regulation, pain sensation, mood, and sleep.
CB2 receptors are primarily found on cells in the immune system and its associated structures. When activated, they stimulate a response that fights inflammation, which can reduce pain and minimize damage to tissues.
How do these Receptors Work? Cannabinoids help coordinate and regulate how we feel and think by binding with the endocannabinoid system’s CB1 and CB2 receptors. Fitting like puzzle pieces, cannabinoids are designed to link together with the cannabinoid receptors. Linking activates the receiving neuron into action, triggering a set of events to pass along the message and carry out a variety of cellular responses needed for homeostasis and healthy functioning.
How long does it take for CBD oil to work? Individual response to cannabidiol (CBD) is just that: completely individual from one person to the next. So how long does it take for CBD oil to work?
Do some people respond more quickly than others? The short answer is, it depends on the person, the product, and the method of consumption. (Remember, CBD from industrial hemp is non-intoxicating, so it doesn’t create a “high” when it’s consumed.) What’s more, a group of individuals consuming the same CBD oil product might all report completely different experiences from one person to the next. How is this possible? Each person has a different experience after sampling CBD oil liposomes. Just as each human is as individual as a fingerprint, our bodies–and ECS–all have unique needs.
Nourishing The Endocannabinoid System The endocannabinoid system (ECS) is a network of receptors, transport molecules, ligands, and enzymes in the bodies of humans and many animals, including dogs. It serves as a master regulator for the entire body, and it helps to support various organ systems. The endocannabinoid system (ECS) is a network of receptors, transport molecules, ligands, and enzymes in the bodies of humans and many animals, including dogs. It serves as a master regulator for the entire body, and it helps to support various organ systems. The ECS wasn’t discovered until 1992. Since then, research has determined that its role in the body is to help maintain homeostasis, which helps us adapt to external stressors. The problem is, in our modern world, most of us have a starving or overstressed ECS that gets out of balance. In other words, we may not be consuming enough cannabinoids in our diets, if we’re getting them at all. What is CBD’s Role in the Endocannabinoid System? CBD relates to the ECS by restoring, bolstering, and balancing the endocannabinoids. When we consume CBD, we’re simply replenishing the cannabinoids needed for our ECS to thrive. In other words, we’re raising the levels of substances that our ECS naturally produces. CBD oil may also alleviate temporary anxiety, inflammation, and mood swings. Some people say that they notice a healthier glow when consuming CBD oil, and other people simply report feeling more like themselves. Others notice a decrease in their levels of nervousness and sleeplessness. “One of the beauties of CBD is its ability to adapt to each situation,” says Dr. Blair. “CBD is like a Boy Scout: always doing the right thing at the right time and in the right place. It’s the smartest molecule in the world.” By supporting the ECS, we can address a wider range of physical and emotional stress with a healthy response to get back to normal quickly. When our bodies are in homeostasis, we’re more likely to notice a sense of well-being, energy, and focus.
How Should I Take CBD For The Fastest Results? The method of delivery is one of the biggest determining factors in how long it will take CBD oil to work. Each method of consumption comes with different levels of bioavailability. So what does that mean? And how long does it take for CBD oil to work in each instance? Bioavailability means how much of a dietary supplement serving absorbs into your body (usually just a fraction of the full amount you ingest). It’s the measure of the serving that reaches the bloodstream. Some CBD oil products have higher bioavailability than others. We recommend always choosing a full-spectrum CBD oil that has been extracted through a non-toxic method like supercritical CO2 extraction. This ensures: All the cannabinoids, terpenes, phytonutrients, antioxidants, and flavonoids that naturally occur in hemp have been preserved in a clean extract When Does CBD Get Into the Bloodstream? Different products deliver CBD to the bloodstream at different rates. Let’s dig into the differences among common methods of delivery.
Method: Dr. Jack's CBD Full Spectrum Oil Time to bloodstream: approx. 2 minutes Method: Dr. Jack's CBD Tinctures Time to bloodstream: approx. 2 minutes Oral Delivery
Method: Dr. Jack's CBD Capsules Time to bloodstream: approx. 1 hour This method of consuming CBD works more slowly because, instead of absorbing through the mucous membranes in your mouth, the CBD must pass through your liver and digestive system. Take CBD capsules with fatty food, which cause the CBD to enter lymphatics, concentrate there on the immune cells, and bypass liver detox. The upside to taking a CBD pill is that the effects can last much longer than oil or tincture delivery–possibly as long as twelve hours. Topical Delivery Method: Dr. Jack's CBD Relief Body Butter Time to bloodstream: no CBD levels in the blood with topical application Topical CBD delivery works differently, in that you won’t get blood levels of CBD. Instead, the CBD molecules are signaling locally to give you fast relief of temporary inflammation, right where you applied the topical. People may feel a difference within about 5 minutes. Choose a CBD topical cream that includes inflammation-fighting essential oils like peppermint to get the most out of your topical CBD experience. Choose the CBD That Works Best for Your Lifestyle In the end, the type of CBD you choose, and how long it takes for CBD oil to work, depends entirely on you. CBD experiences may vary, depending upon your lifestyle, activity, and nutrition. Choose whichever form of CBD delivery best fits with your lifestyle and health needs. What proper serving sizes look like for you may not be exactly what your neighbor needs. There are no known negative effects of consuming CBD products and, according to the World Health Organization, CBD has a very good safety profile.