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Endocannabinoid System

Did You Know?
The endocannabinoid system is responsible for maintaining:

  • Metabolism
  • Pain
  • Appetite
  • Sleep
  • Mood
  • Movement
  • Temperature
  • Memory & Learning
  • Inflammation
  • Neural Development
  • Neuroprotection
  • Cardiovascular Function
  • Digestion
  • Reproduction

Discovered in the 1942, the endocannabinoid system by Dr. Roger Adams, the ( EDC ) is a biological system composed of endocannabinoids that are neurotransmitters that bind to cannabinoid receptors in our mammalian brain and body. CBD the primary cannabinoid found in hemp.

Discovered in 1990, the Cb1 and CB2 receptors are primarily found in cells in the immune system and its associated structures. When activated, they stimulate a response all over the EDC system.

Cannabinoids like cannabidiol (CBD) and tetrahydrocannabinol (THC) are able to elicit t healing effects by interacting with the body’s endocannabinoid system. The EDC gets lite up. The system, integral to our physiologies, is responsible for regulating body processes, such as pain sensation, immune response, anxiety, sleep, mood, appetite, metabolism, memory, and more.

The endocannabinoid system is made up of two types of receptors that are configured to accept cannabinoids. These cannabinoid receptors – CB1 and CB2 – are located on cells throughout the body.

CB1 Receptors

Discovered by scientists in 1990, CB1 receptors are primarily found in the brain and central nervous system, but are also present in the lungs, liver, kidneys, and reproductive organs. These receptors interact with CBD ignite the EDC.

CB1receptors have also been found been found to play a role in memory processing, motor regulation, appetite, pain sensation, mood, and sleep.

The activation of the CB1 receptors have also been linked to neuroprotective responses, suggesting the cannabinoids with a higher affinity for CB1 receptors could help in the prevention and treatment of neurodegenerative conditions like multiple sclerosisAlzheimer’s disease, and Parkinson’s disease.

CB2 Receptors

CB2 receptors, discovered by researchers in 1993, are found primarily on cells in the immune system and its associated structures.

When CB2 receptors are activated, they stimulate a response that fights inflammation, which in turn reduces pain and minimizes damage to tissues.

These anti-inflammatory effects have been found to be beneficial for treating inflammation-related conditions like arthritisCrohn’s disease and inflammatory bowel syndrome.

Cannabinoids’ Relationship to the CB2 and CB2 Receptors

Cannabinoids help coordinate and regulate everything we feel, think, and do by binding or interacting with the endocannabinoid system’s CB1 and CB2 receptors. Like a key fits to a lock, cannabinoids are designed to link together with the cannabinoid receptors. When they link, it spurs the receiving neuron into action, triggering a set of events to pass along the message and carry out a variety of cellular responses needed for homeostasis and healthy functioning.

Overall, significant research must still be done and is being done to better understand the impact of the interaction between cannabinoids and the CB1  and CB2 receptors. Scientists are still investigating how supplementing our natural cannabinoid production with plant-based cannabinoids may play a significant therapeutic role in our general health and wellness.

How do these Receptors Work?
Cannabinoids help coordinate and regulate how we feel and think by binding with the endocannabinoid system’s CB1 and CB2 receptors. Fitting like puzzle pieces, cannabinoids are designed to link together with the cannabinoid receptors.

Linking activates the receiving neuron into action, triggering a set of events to pass along the message and carry out a variety of cellular responses needed for homeostasis and healthy functioning.